• Target：
• AIFL

• Gene Name：
• AIFM3

• Protein Name：
• Apoptosis-inducing factor 3

• Human Gene Id：
• 150209

• Human Swiss Prot No：
• Q96NN9

• Mouse Gene Id：
• 72168

• Mouse Swiss Prot No：
• Q3TY86

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59

• Specificity：
• AIFL Polyclonal Antibody detects endogenous levels of AIFL protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• AIFM3;AIFL;Apoptosis-inducing factor 3;Apoptosis-inducing factor-like protein

• Observed Band(KD)：
• 67kD

• Background：
• domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,

• Function：
• domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,

• Subcellular Location：
• Mitochondrion . Does not translocate to the nucleus upon induction of apoptosis.

• Expression：
• Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).

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