• Target：
• ACOT2

• Fields：
• >>Fatty acid elongation;>>Biosynthesis of unsaturated fatty acids;>>Metabolic pathways;>>Ovarian steroidogenesis

• Gene Name：
• ACOT2

• Protein Name：
• Acyl-coenzyme A thioesterase 2 mitochondrial

• Human Gene Id：
• 10965

• Human Swiss Prot No：
• P49753

• Mouse Swiss Prot No：
• Q9QYR9

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human ACOT2. AA range:171-220

• Specificity：
• ACOT2 Polyclonal Antibody detects endogenous levels of ACOT2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ACOT2;PTE2;PTE2A;Acyl-coenzyme A thioesterase 2; mitochondrial;Acyl-CoA thioesterase 2;Acyl-coenzyme A thioester hydrolase 2a;CTE-Ia;Long-chain acyl-CoA thioesterase 2;ZAP128

• Observed Band(KD)：
• 53kD

• Background：
• This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],

• Function：
• catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate.,caution:Was originally (PubMed:10944470) thought to be peroxisomal but was later shown (PubMed:16940157) to be mitochondrial.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs.,similarity:Belongs to the C/M/P thioester hydrolase family.,tissue specificity:Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.,

• Subcellular Location：
• Mitochondrion .

• Expression：
• Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.

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