ABHD4 Polyclonal Antibody
- Catalog No.:YT0060
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- ABHD4
- Gene Name:
- ABHD4
- Protein Name:
- Abhydrolase domain-containing protein 4
- Human Gene Id:
- 63874
- Human Swiss Prot No:
- Q8TB40
- Mouse Gene Id:
- 105501
- Mouse Swiss Prot No:
- Q8VD66
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ABHD4. AA range:251-300
- Specificity:
- ABHD4 Polyclonal Antibody detects endogenous levels of ABHD4 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- ABHD4;Abhydrolase domain-containing protein 4;Alpha/beta-hydrolase 4;Lyso-N-acylphosphatidylethanolamine lipase
- Molecular Weight(Da):
- 39kD
- Background:
- caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,
- Function:
- caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,
- Subcellular Location:
- endoplasmic reticulum membrane,lipid particle,
- Expression:
- Cervix,
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- Antibody-FAQs
- Products Images
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ABHD4 Antibody. The picture on the right is blocked with the synthesized peptide.