• Target：
• RCC1

• Gene Name：
• RCC1 CHC1

• Protein Name：
• RCC1 (Ser11)

• Human Gene Id：
• 1104

• Human Swiss Prot No：
• P18754

• Mouse Gene Id：
• 100088

• Mouse Swiss Prot No：
• Q8VE37

• Immunogen：
• Synthesized phosho peptide around human RCC1 (Ser11)

• Specificity：
• This antibody detects endogenous levels of Human RCC1 (phospho-Ser11)

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)

• Observed Band(KD)：
• 45kD

• Function：
• disease:Patients with Raynaud disease produce antibodies that bind to RCC1.,function:Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA.,similarity:Contains 7 RCC1 repeats.,subcellular location:Becomes dispersed throughout the cytoplasm during mitosis.,

• Subcellular Location：
• Nucleus . Chromosome . Cytoplasm . Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449). .

• Expression：
• Brain,Breast,Epithelium,Eye,Muscle,Testis,

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