• Target：
• PPIG

• Gene Name：
• PPIG

• Protein Name：
• PPIG (Ser376)

• Human Gene Id：
• 9360

• Human Swiss Prot No：
• Q13427

• Mouse Gene Id：
• 228005

• Mouse Swiss Prot No：
• A2AR02

• Rat Gene Id：
• 83624

• Rat Swiss Prot No：
• O55035

• Immunogen：
• Synthesized phosho peptide around human PPIG (Ser376)

• Specificity：
• This antibody detects endogenous levels of Human Mouse Rat PPIG (phospho-Ser376)

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G)

• Observed Band(KD)：
• 82kD

• Function：
• catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,domain:The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.,enzyme regulation:Cyclosporin A (CsA)-sensitive.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcell

• Subcellular Location：
• Nucleus matrix . Nucleus speckle . Colocalizes with RNA splicing factors at nuclear speckles. .

• Expression：
• Ubiquitous.

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