GATA-3 (phospho Ser308) Polyclonal Antibody

    • Catalog No.:YP1179
    • Applications:WB,IF/ICC,ELISA
    • Reactivity:Human,Mouse
      • Gene Name:
      • GATA3
      • Protein Name:
      • Trans-acting T-cell-specific transcription factor GATA-3
      • Human Gene Id:
      • 2625
      • Human Swiss Prot No:
      • P23771
      • Mouse Swiss Prot No:
      • P23772
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GATA3 around the phosphorylation site of Ser308. AA range:274-323
      • Specificity:
      • Phospho-GATA-3 (S308) Polyclonal Antibody detects endogenous levels of GATA-3 protein only when phosphorylated at S308.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3
      • MolecularWeight(Da):
      • 47916
      • Background:
      • GATA binding protein 3(GATA3) Homo sapiens This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009],
      • Function:
      • disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells.,
      • Subcellular Location:
      • nuclear chromatin,nucleus,nucleoplasm,transcription factor complex,nucleolus,
      • Expression:
      • Cervix,Placenta,T-cell,
      • Products Images
      • Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using GATA3 (Phospho-Ser308) Antibody
      • Immunofluorescence analysis of HUVEC cells, using GATA3 (Phospho-Ser308) Antibody. The picture on the right is blocked with the phospho peptide.