DOR-1 (phospho Ser363) Polyclonal Antibody

    • Catalog No.:YP0626
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • DOR-1
      • Fields:
      • >>cGMP-PKG signaling pathway;>>Sphingolipid signaling pathway;>>Neuroactive ligand-receptor interaction
      • Gene Name:
      • OPRD1
      • Protein Name:
      • Delta-type opioid receptor
      • Human Gene Id:
      • 4985
      • Human Swiss Prot No:
      • P41143
      • Mouse Swiss Prot No:
      • P32300
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human Opioid Receptor-delta around the phosphorylation site of Ser363. AA range:323-372
      • Specificity:
      • Phospho-DOR-1 (S363) Polyclonal Antibody detects endogenous levels of DOR-1 protein only when phosphorylated at S363.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • OPRD1;OPRD;Delta-type opioid receptor;D-OR-1;DOR-1
      • Observed Band(KD):
      • 36kD
      • Background:
      • function:Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.,online information:Delta opioid receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with GPRASP1.,
      • Function:
      • function:Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.,online information:Delta opioid receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with GPRASP1.,
      • Subcellular Location:
      • Cell membrane ; Multi-pass membrane protein .
      • Expression:
      • Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.
      • Products Images
      • Western Blot analysis of 293 cells using Phospho-DOR-1 (S363) Polyclonal Antibody
      • Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Opioid Receptor-delta (Phospho-Ser363) Antibody
      • Immunohistochemistry analysis of paraffin-embedded human brain, using Opioid Receptor-delta (Phospho-Ser363) Antibody. The picture on the right is blocked with the phospho peptide.
      • Western blot analysis of lysates from 293 cells treated with TSA 400nM 24h, using Opioid Receptor-delta (Phospho-Ser363) Antibody. The lane on the right is blocked with the phospho peptide.