DR1 rabbit pAb

  • Catalog No.：YN7248
  • Applications：WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • DR1
    • Gene Name：
    • DR1
    • Protein Name：
    • Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)
    • Human Gene Id：
    • 1810
    • Human Swiss Prot No：
    • Q01658
    • Mouse Swiss Prot No：
    • Q91WV0
    • Immunogen：
    • Synthesized peptide derived from human DR1
    • Specificity：
    • This antibody detects endogenous levels of DR1 at Human, Mouse,Rat
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Molecular Weight(Da)：
    • 19kD
    • Function：
    • The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
    • Subcellular Location：
    • Nucleus.

    Attributes

    • Code：
    • YN7248
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 160 / 280 / 450
    • Delivery：
    • 2024-07-26
    Order

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