ADHFE1 rabbit pAb
- Catalog No.:YN7245
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- ADHFE1
- Gene Name:
- ADHFE1 HMFT2263
- Protein Name:
- Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)
- Human Gene Id:
- 137872
- Human Swiss Prot No:
- Q8IWW8
- Mouse Gene Id:
- 76187
- Mouse Swiss Prot No:
- Q8R0N6
- Rat Gene Id:
- 362474
- Rat Swiss Prot No:
- Q4QQW3
- Immunogen:
- Synthesized peptide derived from human ADHFE1
- Specificity:
- This antibody detects endogenous levels of ADHFE1 at Human, Mouse,Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 51kD
- Function:
- Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.
- Subcellular Location:
- Mitochondrion .
- Expression:
- Only expressed in adult liver.
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