ADHFE1 rabbit pAb

  • Catalog No.:YN7245
  • Applications:WB
  • Reactivity:Human;Mouse;Rat
    • Target:
    • ADHFE1
    • Gene Name:
    • ADHFE1 HMFT2263
    • Protein Name:
    • Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)
    • Human Swiss Prot No:
    • Q8IWW8
    • Mouse Swiss Prot No:
    • Q8R0N6
    • Immunogen:
    • Synthesized peptide derived from human ADHFE1
    • Specificity:
    • This antibody detects endogenous levels of ADHFE1 at Human, Mouse,Rat
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Molecular Weight(Da):
    • 51kD
    • Function:
    • Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.
    • Subcellular Location:
    • Mitochondrion .
    • Expression:
    • Only expressed in adult liver.