UAP1 rabbit pAb

  • Catalog No.:YN7244
  • Applications:WB
  • Reactivity:Human;Mouse
    • Target:
    • UAP1
    • Gene Name:
    • UAP1 SPAG2
    • Protein Name:
    • UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX) (Sperm-associated antigen 2) [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.-) (AGX-1); UDP-N-acetylglucosamine pyrophospho
    • Human Gene Id:
    • 6675
    • Human Swiss Prot No:
    • Q16222
    • Mouse Swiss Prot No:
    • Q91YN5
    • Immunogen:
    • Synthesized peptide derived from human UAP1
    • Specificity:
    • This antibody detects endogenous levels of UAP1 at Human, Mouse
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Molecular Weight(Da):
    • 57kD
    • Function:
    • Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
    • Subcellular Location:
    • Cytoplasm. In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
    • Expression:
    • Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.