PHF20 rabbit pAb

  • Catalog No.:YN7242
  • Applications:WB
  • Reactivity:Human;Mouse
    • Target:
    • PHF20
    • Gene Name:
    • PHF20 C20orf104 GLEA2 HCA58 NZF TZP
    • Protein Name:
    • PHD finger protein 20 (Glioma-expressed antigen 2) (Hepatocellular carcinoma-associated antigen 58) (Novel zinc finger protein) (Transcription factor TZP)
    • Human Swiss Prot No:
    • Q9BVI0
    • Mouse Swiss Prot No:
    • Q8BLG0
    • Immunogen:
    • Synthesized peptide derived from human PHF20
    • Specificity:
    • This antibody detects endogenous levels of PHF20 at Human, Mouse
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Molecular Weight(Da):
    • 111kD
    • Function:
    • Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
    • Subcellular Location:
    • Nucleus .
    • Expression:
    • Expressed in heart, kidney, liver, lung, pancreas, placenta, spleen and testis. Not expressed in brain, skeletal muscle, colon, ovary, prostate, small intestine and thymus. Expressed in colon and ovary cancer cell lines while it is not expressed in the respective normal tissues.