Nucleoside phosphorylase rabbit pAb

  • Catalog No.:YN7227
  • Applications:WB
  • Reactivity:Human;Mouse;Rat
    • Target:
    • PNP
    • Gene Name:
    • PNP NP
    • Protein Name:
    • Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
    • Human Gene Id:
    • 4860
    • Human Swiss Prot No:
    • P00491
    • Mouse Swiss Prot No:
    • P23492
    • Immunogen:
    • Synthesized peptide derived from human Nucleoside phosphorylase
    • Specificity:
    • This antibody detects endogenous levels of Nucleoside phosphorylase at Human, Mouse,Rat
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Molecular Weight(Da):
    • 32kD
    • Function:
    • Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate . Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine .
    • Subcellular Location:
    • Cytoplasm .
    • Expression:
    • Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.