Nucleoside phosphorylase rabbit pAb
- Catalog No.:YN7227
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- PNP
- Gene Name:
- PNP NP
- Protein Name:
- Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
- Human Gene Id:
- 4860
- Human Swiss Prot No:
- P00491
- Mouse Gene Id:
- 18950
- Mouse Swiss Prot No:
- P23492
- Rat Swiss Prot No:
- P85973
- Immunogen:
- Synthesized peptide derived from human Nucleoside phosphorylase
- Specificity:
- This antibody detects endogenous levels of Nucleoside phosphorylase at Human, Mouse,Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 32kD
- Function:
- Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate . Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine .
- Subcellular Location:
- Cytoplasm .
- Expression:
- Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.
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