Iba1 Polyclonal Antibody

  • Catalog No.：YN2165
  • Applications：WB;IF;ELISA
  • Reactivity：Human;Rat;Mouse
    • Target：
    • AIF1
    • Gene Name：
    • AIF1 G1 IBA1
    • Protein Name：
    • Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)
    • Human Gene Id：
    • 199
    • Human Swiss Prot No：
    • P55008
    • Mouse Swiss Prot No：
    • O70200
    • Immunogen：
    • Synthesized peptide derived from part region of human protein
    • Specificity：
    • AIF1 Polyclonal Antibody detects endogenous levels of protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500 - 1:2000. ELISA: 1:5000. IF 1:100-300 Not yet tested in other applications.
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Observed Band(KD)：
    • 16kD
    • Background：
    • This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],
    • Function：
    • function:May play a role in macrophage activation and function.,PTM:Phosphorylated on serine residues.,similarity:Contains 2 EF-hand domains.,
    • Subcellular Location：
    • Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. .
    • Expression：
    • Detected in T-lymphocytes and peripheral blood mononuclear cells.

    Attributes

    • Code：
    • YN2165
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-12-22
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