LTOR3 Polyclonal Antibody

    • Catalog No.:YN1616
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • LTOR3
      • Fields:
      • >>MAPK signaling pathway;>>mTOR signaling pathway
      • Gene Name:
      • LAMTOR3 MAP2K1IP1 MAPKSP1 PRO2783
      • Protein Name:
      • Ragulator complex protein LAMTOR3 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3) (MEK-binding partner 1) (Mp1) (Mitogen-activated protein kinase kinase 1-interacting protein 1) (Mito
      • Human Gene Id:
      • 8649
      • Human Swiss Prot No:
      • Q9UHA4
      • Mouse Swiss Prot No:
      • O88653
      • Immunogen:
      • Synthesized peptide derived from human protein . at AA range: 30-110
      • Specificity:
      • LTOR3 Polyclonal Antibody detects endogenous levels of protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000 ELISA 1:5000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Observed Band(KD):
      • 13kD
      • Background:
      • This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011],
      • Function:
      • function:Adapter protein that enhances the efficiency of the MAP kinase cascade. Facilitates the activation of MAPK2.,similarity:Belongs to the MAPKSP1 family.,subunit:Interacts with MAP2K1 and MAPK2. Interacts with MORG1 (By similarity). Heterodimer with MAPBPIP.,
      • Subcellular Location:
      • Late endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
      • Expression:
      • Brain,Dendritic cell,Fetal liver,Liver,Lung
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night