CCG8 Polyclonal Antibody
- Catalog No.:YN1524
- Applications:WB;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- CCG8
- Fields:
- >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
- Gene Name:
- CACNG8 CACNG6
- Protein Name:
- Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage-gated calcium channel gamma-8 subunit) (Transmembrane AMPAR regulatory protein gamma-8) (TARP gamma-8)
- Human Gene Id:
- 59283
- Human Swiss Prot No:
- Q8WXS5
- Mouse Swiss Prot No:
- Q8VHW2
- Rat Swiss Prot No:
- Q8VHW5
- Immunogen:
- Synthesized peptide derived from human protein . at AA range: 140-220
- Specificity:
- CCG8 Polyclonal Antibody detects endogenous levels of protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000 ELISA 1:5000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Observed Band(KD):
- 46kD
- Background:
- calcium voltage-gated channel auxiliary subunit gamma 8(CACNG8) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for this gene is believed to initiate translation from a non-AUG (CUG) start codon. [provided by RefSeq, Dec 2010],
- Function:
- function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic density membrane .
- Expression:
- Detected in heart left ventricle.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night