Calponin-1 (ABT133) mouse mAb (Ready to Use)
- Catalog No.:YM6827R
- Applications:IHC
- Reactivity:Human;
- Target:
- Calponin-1
- Gene Name:
- CNN1
- Protein Name:
- Calponin-1
- Human Gene Id:
- 1264
- Human Swiss Prot No:
- P51911
- Immunogen:
- Synthesized peptide derived from human Calponin-1 AA range: 100-200
- Specificity:
- The antibody can specifically recognize human and mouse calponin-1 protein.
- Formulation:
- The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
- Source:
- Mouse, Monoclonal/IgG2a, kappa
- Dilution:
- Ready to use for IHC
- Purification:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- Storage Stability:
- 2°C to 8°C/1 year
- Other Name:
- Calponin-1 (Basic calponin;Calponin H1, smooth muscle)
- Function:
- function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,
- Subcellular Location:
- Cytoplasmic
- Expression:
- Smooth muscle, and tissues containing significant amounts of smooth muscle.
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- Antibody-FAQs
- Products Images
- Human appendix tissue was stained with anti-calponin-1(ABT133) antibody.
- Human smooth muscle tissue was stained with anti-calponin-1(ABT133) antibody.