• Target：
• Calponin-1

• Gene Name：
• CNN1

• Protein Name：
• Calponin-1

• Human Gene Id：
• 1264

• Human Swiss Prot No：
• P51911

• Immunogen：
• Synthesized peptide derived from human Calponin-1 AA range: 100-200

• Specificity：
• The antibody can specifically recognize human and mouse calponin-1 protein.

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Mouse, Monoclonal/IgG2a, kappa

• Dilution：
• IHC 1:200-400. ELISA 1:500-5000

• Purification：
• The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Calponin-1 (Basic calponin;Calponin H1, smooth muscle)

• Molecular Weight(Da)：
• 33kD

• Observed Band(KD)：
• 34kD

• Function：
• function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,subunit:Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.,tissue specificity:Smooth muscle, and tissues containing significant amounts of smooth muscle.,

• Subcellular Location：
• Cytoplasmic

• Expression：
• Smooth muscle, and tissues containing significant amounts of smooth muscle.

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