• Target：
• SLC2A1

• Gene Name：
• SLC2A1 GLUT1

• Protein Name：
• Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter)

• Human Gene Id：
• 6513

• Human Swiss Prot No：
• P11166

• Mouse Gene Id：
• 20525

• Mouse Swiss Prot No：
• P17809

• Immunogen：
• Synthesized peptide derived from human GLUT-1 AA range: 400-492

• Specificity：
• This antibody detects endogenous levels of GLUT-1 protein.

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Mouse, Monoclonal/IgG

• Dilution：
• WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000

• Purification：
• Protein G

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 54kD

• Observed Band(KD)：
• 54kD

• Background：
• solute carrier family 2 member 1(SLC2A1) Homo sapiens This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013],

• Function：
• Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake . Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses . Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain . In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).

• Subcellular Location：
• Membranous

• Expression：
• Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.

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