• Target：
• LALBA

• Fields：
• >>Galactose metabolism;>>Metabolic pathways

• Gene Name：
• LALBA

• Protein Name：
• Alpha-lactalbumin

• Human Gene Id：
• 3906

• Human Swiss Prot No：
• P00709

• Mouse Gene Id：
• 16770

• Mouse Swiss Prot No：
• P29752

• Rat Gene Id：
• 24528

• Rat Swiss Prot No：
• P00714

• Immunogen：
• Synthetic Peptide of alpha Lactalbumin

• Specificity：
• The antibody detects endogenous alpha Lactalbumin proteins.

• Formulation：
• PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:1000 IF 1:200 IHC 1:50-300

• Purification：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Alpha-lactalbumin (Lactose synthase B protein) (Lysozyme-like protein 7)

• Observed Band(KD)：
• 16kD

• Background：
• This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008],

• Function：
• function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.,similarity:Belongs to the glycosyl hydrolase 22 family.,subunit:Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).,tissue specificity:Mammary gland specific. Secreted in milk.,

• Subcellular Location：
• Secreted.

• Expression：
• Mammary gland specific. Secreted in milk.

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