Cyclophilin B Monoclonal Antibody(2B10), Biotin Conjugated

  • Catalog No.：YM2023
  • Applications：IF;WB;IHC;
  • Reactivity：Human;Rat;Mouse
    • Target：
    • Cyclophilin B
    • Gene Name：
    • PPIB
    • Protein Name：
    • Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)
    • Human Gene Id：
    • 5479
    • Human Swiss Prot No：
    • P23284
    • Specificity：
    • Cyclophilin B Monoclonal Antibody(2B10) Biotin conjugated specially designed for your WB or IHC analysis.
    • Formulation：
    • Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
    • Source：
    • Monoclonal, Mouse IgG
    • Dilution：
    • Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-2000, IHC 1:50-300.
    • Purification：
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1mg/ml
    • Storage Stability：
    • Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezi
    • Other Name：
    • Cyclophilin B
    • Background：
    • The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009],
    • Function：
    • catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,caution:It is uncertain whether Met-1 or Met-9 is the initiator.,enzyme regulation:Cyclosporin A (CsA) inhibits CYPB.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
    • Subcellular Location：
    • Virion . (Microbial infection).; Endoplasmic reticulum lumen . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
    • Expression：
    • Brain,Fetal brain cortex,Prostate,Skin,

    Attributes

    • Code：
    • YM2023
    • Size
    • 50μL / 100μL / 500μL
    • Price$：
    • 112 / 192 / 840
    • Delivery：
    • 2024-12-08
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