COX IV Monoclonal Antibody(6C8), AbFluor 488 Conjugated

  • Catalog No.：YM2006
  • Applications：WB;IHC;IF;
  • Reactivity：Human;Rat;Mouse
    • Target：
    • COX IV
    • Fields：
    • >>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
    • Gene Name：
    • COX4I1
    • Protein Name：
    • Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
    • Human Gene Id：
    • 1327
    • Human Swiss Prot No：
    • P13073
    • Specificity：
    • COX IV Monoclonal Antibody(6C8) AbFluor™ 488 Conjugated specially designed for your Immunofluorescence analysis.
    • Formulation：
    • Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
    • Source：
    • Monoclonal, Mouse IgG1
    • Dilution：
    • Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300, IF 1:200 .
    • Purification：
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1mg/ml
    • Storage Stability：
    • Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezi
    • Other Name：
    • COX4I1
    • Background：
    • Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
    • Function：
    • function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase IV family.,tissue specificity:Ubiquitous.,
    • Subcellular Location：
    • Mitochondrion inner membrane ; Single-pass membrane protein .
    • Expression：
    • Ubiquitous.

    Attributes

    • Code：
    • YM2006
    • Size
    • 50μL / 100μL / 500μL
    • Price$：
    • 112 / 192 / 840
    • Delivery：
    • 2024-12-08
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