• Target：
• RPA70

• Fields：
• >>DNA replication;>>Nucleotide excision repair;>>Mismatch repair;>>Homologous recombination;>>Fanconi anemia pathway

• Gene Name：
• rpa70

• Human Gene Id：
• 6117

• Human Swiss Prot No：
• P27694

• Mouse Swiss Prot No：
• Q8VEE4

• Immunogen：
• Purified recombinant human RPA70 protein fragments expressed in E.coli.

• Specificity：
• This antibody detects endogenous levels of RPA70 and does not cross-react with related proteins.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• wb dilution 1:1000 icc dilution 1:100

• Purification：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Dmrpa1;Drosophila Replication Protein A;DRPA;DSSB;HSSB;Human single stranded DNA binding protein;MST075;MSTP075;p70;REPA 1;REPA1;Replication factor A;Replication factor A protein 1;Replication protein A 70 kDa DNA-binding subunit;Replication protein A 70kDa DNA binding subunit;Replication protein A1 (70kD);Replication protein A1 (70kD);Replication protein A1 70kDa;Replication protein A1;RF A;RF-A protein 1;RFA;RFA1_HUMAN;RP A;RP-A p70;RPA 1;RPA 70;RPA;RPA1;Single stranded binding protein 70;Single stranded DNA binding protein;Single-stranded DNA-binding protein;Ssb70.

• Observed Band(KD)：
• 70kD

• Background：
• function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

• Function：
• function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

• Subcellular Location：
• Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .

• Expression：
• Aorta,Aortic endothelium,Lung carcinoma,Uterus,

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