• Target：
• Phostensin

• Gene Name：
• ppp1r18

• Human Gene Id：
• 170954

• Human Swiss Prot No：
• Q6NYC8

• Mouse Swiss Prot No：
• Q8BQ30

• Immunogen：
• Purified recombinant human Phostensin protein fragments expressed in E.coli.

• Specificity：
• This antibody detects endogenous levels of Phostensin and does not cross-react with related proteins.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• wb 1:200

• Purification：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• HKMT1098;KIAA1949;Protein phosphatase 1 F actin cytoskeleton targeting subunit.

• Observed Band(KD)：
• 120kD

• Background：
• Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008],

• Function：
• function:May target protein phosphatase 1 to F-actin cytoskeleton.,subunit:Interacts with Protein phosphatase 1 (PP1).,tissue specificity:Predominantly expressed in leukocytes and spleen.,

• Subcellular Location：
• [Isoform 1]: Cytoplasm, cytoskeleton .; [Isoform 4]: Cytoplasm, cytoskeleton .

• Expression：
• Isoform 4 is predominantly expressed in leukocytes and spleen.

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