NF-1C Monoclonal Antibody
- Catalog No.:YM1064
- Applications:WB
- Reactivity:Human;Mouse;Rat;Bovine;Chicken;Pig
- Target:
- NFIC
- Gene Name:
- NFIC
- Protein Name:
- Nuclear factor 1 C-type
- Human Gene Id:
- 4782
- Human Swiss Prot No:
- P08651
- Mouse Gene Id:
- 18029
- Mouse Swiss Prot No:
- P70255
- Immunogen:
- Purified recombinant human NF-1C protein fragments expressed in E.coli.
- Specificity:
- NF-1C Monoclonal Antibody detects endogenous levels of NF-1C protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Monoclonal, Mouse
- Dilution:
- WB 1:1000 - 1:2000. Not yet tested in other applications.
- Purification:
- Affinity purification
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- NFIC;NFI;Nuclear factor 1 C-type;NF1-C;Nuclear factor 1/C;CCAAT-box-binding transcription factor;CTF;Nuclear factor I/C;NF-I/C;NFI-C;TGGCA-binding protein
- Molecular Weight(Da):
- 56kD
- Background:
- The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
- Function:
- function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.,similarity:Belongs to the CTF/NF-I family.,similarity:Contains 1 CTF/NF-I DNA-binding domain.,subunit:Binds DNA as a homodimer.,
- Subcellular Location:
- Nucleus.
- Expression:
- Epithelium,Uterus,
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- Antibody-FAQs
- Products Images
- Western Blot analysis using NF-1C Monoclonal Antibody against HeLa nuclear extract.