• Target：
• THAP11

• Gene Name：
• THAP11

• Protein Name：
• THAP domain-containing protein 11

• Human Gene Id：
• 57215

• Human Swiss Prot No：
• Q96EK4

• Mouse Swiss Prot No：
• Q9JJD0

• Immunogen：
• Purified recombinant fragment of human THAP11 expressed in E. Coli.

• Specificity：
• THAP11 Monoclonal Antibody detects endogenous levels of THAP11 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• THAP11;HRIHFB2206;THAP domain-containing protein 11

• Molecular Weight(Da)：
• 34kD

• References：
• 1. Genomics. 1993 Jun;16(3):572-9.
  2. Cell. 2008 Jun 27;133(7):1162-74.
  3. Cell Death Differ. 2009 Mar;16(3):395-405.

• Background：
• The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008],

• Function：
• function:Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.,polymorphism:The length of the poly-Gln region is variable in the population.,similarity:Belongs to the THAP11 family.,similarity:Contains 1 THAP-type zinc finger.,subcellular location:May be regulated by shuttling of the protein between the cytoplasm and nucleus.,subunit:Interacts (via coiled coil domain) with HCFC1.,

• Subcellular Location：
• Nucleus . Cytoplasm . May be regulated by shuttling of the protein between the cytoplasm and nucleus. .

• Expression：
• Brain,Neuroblastoma,Uterus,

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