Calnexin protein
- Catalog No.:YD0118
- Applications:WB;SDS-PAGE
- Reactivity:Human
- Gene Name:
- CANX
- Protein Name:
- Calnexin protein
- Sequence:
- Amino acid: 19-236, with his-MBP tag.
- Human Gene Id:
- 821
- Human Swiss Prot No:
- P27824
- Mouse Swiss Prot No:
- P35564
- Formulation:
- Liquid in PBS
- Source:
- E.coli
- Dilution:
- WB 1:500-2000
- Concentration:
- SDS-PAGE >90%
- Storage Stability:
- -20°C/6 month,-80°C for long storage
- Other Name:
- Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
- Background:
- function:Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.,online information:Calnexin entry,similarity:Belongs to the calreticulin family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
- Function:
- protein folding, protein localization, protein secretion, protein transport, secretion by cell, establishment of protein localization, secretion,
- Subcellular Location:
- Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
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