Calnexin protein

    • Catalog No.:YD0118
    • Applications:WB;SDS-PAGE
    • Reactivity:Human
      • Gene Name:
      • CANX
      • Protein Name:
      • Calnexin protein
      • Sequence:
      • Amino acid: 19-236, with his-MBP tag.
      • Human Gene Id:
      • 821
      • Human Swiss Prot No:
      • P27824
      • Mouse Swiss Prot No:
      • P35564
      • Formulation:
      • Liquid in PBS
      • Source:
      • E.coli
      • Dilution:
      • WB 1:500-2000
      • Concentration:
      • SDS-PAGE >90%
      • Storage Stability:
      • -20°C/6 mouth,-80°C for long storage
      • Other Name:
      • Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
      • Background:
      • function:Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.,online information:Calnexin entry,similarity:Belongs to the calreticulin family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
      • Function:
      • protein folding, protein localization, protein secretion, protein transport, secretion by cell, establishment of protein localization, secretion,
      • Subcellular Location:
      • Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
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