HO-1 protein

    • Catalog No.：YD0037
    • Applications：WB;SDS-PAGE
    • Reactivity：Human
      • Gene Name：
      • HMOX1 HO HO1
      • Protein Name：
      • HO-1 protein
      • Sequence：
      • Amino acid: 175-266, with his-MBP tag.
      • Human Gene Id：
      • 3162
      • Human Swiss Prot No：
      • P09601
      • Mouse Swiss Prot No：
      • P14901
      • Formulation：
      • Liquid in PBS
      • Source：
      • E.coli
      • Dilution：
      • WB 1:500-2000
      • Concentration：
      • SDS-PAGE >90%
      • Storage Stability：
      • -20°C/6 month,-80°C for long storage
      • Other Name：
      • Heme oxygenase 1 (HO-1) (EC 1.14.99.3)
      • Background：
      • catalytic activity:Heme + 3 AH(2) + 3 O(2) = biliverdin + Fe(2+) + CO + 3 A + 3 H(2)O.,function:Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.,induction:Heme oxygenase 1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA.,similarity:Belongs to the heme oxygenase family.,
      • Function：
      • response to reactive oxygen species, angiogenesis, blood vessel development, response to hypoxia, regulation of cytokine production, negative regulation of cytokine production, endothelial cell proliferation, vasculature development, healing during inflammatory response, negative regulation of immune system process, regulation of leukocyte migration, negative regulation of leukocyte migration, regulation of leukocyte activation, negative regulation of leukocyte activation, regulation of immune effector process, negative regulation of immune effector process,regulation of production of molecular mediator of immune response, negative regulation of production of molecular mediator of immune response, regulation of leukocyte mediated immunity, regulation of cytokine production during immune response, negative regulation of cytokine production during immune response, regulation of myeloid leu
      • Subcellular Location：
      • Endoplasmic reticulum membrane ; Single-pass type IV membrane protein ; Cytoplasmic side .
      • Expression：
      • Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level).
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      Attributes

      • Code：
      • YD0037
      • Size
      • 100μg
      • Price$：
      • 280
      • Delivery：
      • 2024-08-22
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