ERK3 protein

    • Catalog No.：YD0029
    • Applications：WB;SDS-PAGE
    • Reactivity：Human
      • Gene Name：
      • MAPK6
      • Protein Name：
      • ERK3 protein
      • Sequence：
      • Amino acid: 299-526, with his-MBP tag.
      • Human Gene Id：
      • 5597
      • Human Swiss Prot No：
      • Q16659
      • Mouse Swiss Prot No：
      • Q61532
      • Formulation：
      • Liquid in PBS
      • Source：
      • E.coli
      • Dilution：
      • WB 1:500-2000
      • Concentration：
      • SDS-PAGE >90%
      • Storage Stability：
      • -20°C/6 month,-80°C for long storage
      • Other Name：
      • Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
      • Background：
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by threonine and tyrosine phosphorylation.,function:Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.,PTM:Dually phosphorylated on Thr-626 and Tyr-628, which activates the enzyme.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.,
      • Function：
      • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle,phosphorylation,
      • Subcellular Location：
      • Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .
      • Expression：
      • Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
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      Attributes

      • Code：
      • YD0029
      • Size
      • 100μg
      • Price$：
      • 280
      • Delivery：
      • 2024-08-22
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