Cleaved-Cathepsin Z (L62) Polyclonal Antibody

    • Catalog No.：YC0046
    • Applications：WB;ELISA
    • Reactivity：Human;Monkey
      • Target：
      • Cathepsin Z
      • Fields：
      • >>Lysosome;>>Apoptosis
      • Gene Name：
      • CTSZ
      • Protein Name：
      • Cathepsin Z
      • Human Gene Id：
      • 1522
      • Human Swiss Prot No：
      • Q9UBR2
      • Mouse Swiss Prot No：
      • Q9WUU7
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from human CATZ. AA range:43-92
      • Specificity：
      • Cleaved-Cathepsin Z (L62) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin Z protein resulting from cleavage adjacent to L62.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • CTSZ;Cathepsin Z;Cathepsin P;Cathepsin X
      • Observed Band(KD)：
      • 27kD
      • Background：
      • The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008],
      • Function：
      • catalytic activity:Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.,function:Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.,similarity:Belongs to the peptidase C1 family.,tissue specificity:Widely expressed.,
      • Subcellular Location：
      • Lysosome.
      • Expression：
      • Widely expressed.
      • Products Images
      • Western Blot analysis of various cells using Cleaved-Cathepsin Z (L62) Polyclonal Antibody
      • Western blot analysis of lysates from COS7 cells, treated with etoposide 25uM 1h, using CATZ (Cleaved-Leu62) Antibody. The lane on the right is blocked with the synthesized peptide.

      Attributes

      • Code：
      • YC0046
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-05-03
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