• Target：
• Cathepsin Z

• Fields：
• >>Lysosome;>>Apoptosis

• Gene Name：
• CTSZ

• Protein Name：
• Cathepsin Z

• Human Gene Id：
• 1522

• Human Swiss Prot No：
• Q9UBR2

• Mouse Swiss Prot No：
• Q9WUU7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human CATZ. AA range:43-92

• Specificity：
• Cleaved-Cathepsin Z (L62) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin Z protein resulting from cleavage adjacent to L62.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CTSZ;Cathepsin Z;Cathepsin P;Cathepsin X

• Observed Band(KD)：
• 27kD

• Background：
• The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008],

• Function：
• catalytic activity:Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.,function:Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.,similarity:Belongs to the peptidase C1 family.,tissue specificity:Widely expressed.,

• Subcellular Location：
• Lysosome.

• Expression：
• Widely expressed.

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