CD64 (PN0651) Nb-FC recombinant antibody

  • Catalog No.:YA0653
  • Applications:FCM;ELISA
  • Reactivity:Human
    • Target:
    • CD64
    • Fields:
    • >>Phagosome;>>Osteoclast differentiation;>>Neutrophil extracellular trap formation;>>Hematopoietic cell lineage;>>Fc gamma R-mediated phagocytosis;>>Leishmaniasis;>>Staphylococcus aureus infection;>>Tuberculosis;>>Transcriptional misregulation in cancer;>>Acute myeloid leukemia;>>Systemic lupus erythematosus
    • Gene Name:
    • FCGR1A FCG1 FCGR1 IGFR1
    • Protein Name:
    • High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64)
    • Human Gene Id:
    • 2209
    • Human Swiss Prot No:
    • P12314
    • Mouse Swiss Prot No:
    • P26151
    • Immunogen:
    • Purified recombinant human CD64
    • Specificity:
    • This recombinant monoclonal antibody can detects endogenous levels of CD64 protein.
    • Formulation:
    • Phosphate-buffered solution
    • Source:
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • Dilution:
    • ELISA 1:5000-100000;FCM 1-2μg/Test
    • Purification:
    • Recombinant Expression and Affinity purified
    • Concentration:
    • Please check the information on the tube
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I;Fc-gamma RI;FcRI;Fc-gamma RIA;FcgammaRIa;CD antigen CD64)
    • Observed Band(KD):
    • 45kD
    • Background:
    • This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008],
    • Function:
    • function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.,online information:FCGR1A mutation db,PTM:N-glycosylated.,PTM:Phosphorylated on serine residues.,similarity:Belongs to the immunoglobulin superfamily. FCGR1 family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Stabilized at the cell membrane through interaction with FCER1G.,subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL.,tissue specificity:Monocyte/macrophage specific.,
    • Subcellular Location:
    • Cell membrane ; Single-pass type I membrane protein . Stabilized at the cell membrane through interaction with FCER1G.
    • Expression:
    • Monocyte/macrophage specific.