• Gene Name：
• PDGFA/PDGFB

• Protein Name：
• Platelet-derived growth factor subunit A/Platelet-derived growth factor subunit B

• Human Gene Id：
• 5154/5155

• Human Swiss Prot No：
• P04085/P01127

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• PDGFA;PDGF1;Platelet-derived growth factor subunit A;PDGF subunit A;PDGF-1;Platelet-derived growth factor A chain;Platelet-derived growth factor alpha polypeptide;PDGFB;PDGF2;SIS;Platelet-derived growth factor subunit B;PDGF subu

• Detection Method：
• Colorimetric

• Background：
• domain:The long form contains a basic insert which acts as a cell retention signal.,function:Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.,miscellaneous:A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor.,similarity:Belongs to the PDGF/VEGF growth factor family.,subunit:Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with CSPG4.,

• Function：
• angiogenesis, blood vessel development, response to hypoxia, cell activation, regulation of protein amino acid phosphorylation, hair follicle development, vasculature development, positive regulation of mesenchymal cell proliferation, regulation of DNA replication, chemotaxis, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway,transmembrane receptor protein serine/threonine kinase signaling pathway, transforming growth factor beta receptor signaling pathway, cell-cell signaling, ectoderm development, sensory organ development, response to nutrient,behavior, locomotory behavior, cell proliferation, positive regulation of cell proliferation, epidermis development,response to wounding, response to endogenous stimulus, response to hormone stimulus, negative regulation of biosynth

• Subcellular Location：
• Secreted. Released by platelets upon wounding.

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