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- Human Gas6 ELISA Kit
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Human Gas6 ELISA Kit
- Catalog No.:KE1227
- Applications:ELISA
- Reactivity:Human
- Protein Name:
- Growth arrest-specific protein 6
- Specificity:
- Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- GAS6;AXLLG;Growth arrest-specific protein 6;GAS-6;AXL receptor tyrosine kinase ligand
- Detection Method:
- Colorimetric
- Background:
- function:Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. Plays a role in thrombosis by amplifying platelet aggregation and secretion in response to known agonists.,PTM:Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.,PTM:Isoform 1 is proteolytically processed after secretion to yield a N-terminal 36 kDa protein and a C-terminal 50 kDa protein including the laminin G-like domains which activates AXL.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 2 laminin G-like domains.,similarity:Contains 4 EGF-like domains.,subunit:Heterodimer and heterotetramer with AXL.,tissue specificity:Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen.,
- Function:
- cell proliferation, regeneration, organ regeneration, regulation of growth,
- Subcellular Location:
- Secreted .
- Expression:
- Plasma. Isoform 1 and isoform 2 are widely expressed, isoform 1 being expressed at higher levels than isoform 2 in most tissues. Isoform 2 is the predominant form in spleen.
![](/uploadfiles/PIC/ke1227-elisa.jpg)
- The Human Gas6 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Gas6 proteins within the range of 125-8000 pg/ml.