• Gene Name：
• BMP7

• Protein Name：
• Bone morphogenetic protein 7

• Human Gene Id：
• 655

• Human Swiss Prot No：
• P18075

• Mouse Swiss Prot No：
• P23359

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• BMP7;OP1;Bone morphogenetic protein 7;BMP-7;Osteogenic protein 1;OP-1;Eptotermin alfa

• Detection Method：
• Colorimetric

• Background：
• function:Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.,online information:Bone morphogenetic protein 7 entry,pharmaceutical:Available under the names Osigraft (Stryker). Its use is indicated in the treatment of tibial non-union of at least 9 month duration, secondary to trauma, in skeletally mature patients, in cases where autograft has failed or is unfeasible.,PTM:Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1.,tissue specificity:Expressed in the kidneys and bladder. Lower levels seen in the brain.,

• Function：
• cell morphogenesis, cell morphogenesis involved in differentiation, skeletal system development, ossification, eye development, urogenital system development, formation of primary germ layer, mesoderm formation, morphogenesis of a branching structure, kidney development, epithelial to mesenchymal transition, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, cell motion, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, gastrulation, pattern specification process, axonogenesis, axon guidance, sensory organ develop

• Subcellular Location：
• Secreted.

• Expression：
• Expressed in the kidney and bladder. Lower levels seen in the brain.

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