• Gene Name：
• AGRP

• Protein Name：
• Agouti-related protein

• Human Gene Id：
• 181

• Human Swiss Prot No：
• O00253

• Mouse Swiss Prot No：
• P56473

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• AGRP;AGRT;ART;Agouti-related protein

• Detection Method：
• Colorimetric

• Background：
• disease:Defects in AGRP may be a cause of autosomal dominant obesity [MIM:601665].,domain:The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.,function:Plays a role in weight homeostasis. May play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding.,similarity:Contains 1 agouti domain.,tissue specificity:Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.,

• Function：
• cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway, intracellular signaling cascade, behavior, feeding behavior, adult feeding behavior, response to endogenous stimulus, response to hormone stimulus, hormone-mediated signaling, response to organic substance,adult behavior, cellular response to hormone stimulus, eating behavior,

• Subcellular Location：
• Secreted . Golgi apparatus lumen .

• Expression：
• Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.

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