• Gene Name：
• TIMP2

• Protein Name：
• Metalloproteinase inhibitor 2

• Human Gene Id：
• 7077

• Human Swiss Prot No：
• P16035

• Mouse Swiss Prot No：
• P25785

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• TIMP2;Metalloproteinase inhibitor 2;CSC-21K;Tissue inhibitor of metalloproteinases 2;TIMP-2

• Detection Method：
• Colorimetric

• Background：
• function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.,PTM:The activity of TIMP2 is dependent on the presence of disulfide bonds.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,

• Function：
• regulation of nucleotide metabolic process, negative regulation of cell proliferation, regulation of protein kinase cascade, regulation of cyclic nucleotide metabolic process, regulation of cAMP metabolic process, regulation of cell proliferation, regulation of MAPKKK cascade, regulation of neuron differentiation, regulation of neurogenesis,regulation of nervous system development, regulation of cell development,

• Subcellular Location：
• Secreted.

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