• Gene Name：
• CDH1

• Protein Name：
• Cadherin-1

• Human Gene Id：
• 999

• Human Swiss Prot No：
• P12830

• Mouse Swiss Prot No：
• P09803

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• CDH1;CDHE;UVO;Cadherin-1;CAM 120/80;Epithelial cadherin;E-cadherin;Uvomorulin;CD antigen CD324

• Detection Method：
• Colorimetric

• Function：
• in utero embryonic development, blastocyst development, blastocyst formation, trophectodermal cell differentiation,protein complex assembly, cell adhesion, homophilic cell adhesion, synaptogenesis, response to toxin, embryonic development ending in birth or egg hatching, response to organic substance, regulation of cell death, cell-cell adhesion, diencephalon development, pituitary gland development, biological adhesion, cell projection organization,neuron differentiation, forebrain development, neuron projection development, regulation of intracellular transport,positive regulation of intracellular transport, regulation of protein localization, regulation of intracellular protein transport, endocrine system development, regulation of protein import into nucleus, positive regulation of protein import into nucleus, response to drug, regulation of apoptosis, regulation of transcription fac

• Subcellular Location：
• Cell junction, adherens junction . Cell membrane ; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane.

• Expression：
• Non-neural epithelial tissues.

Correlation analysis between the parameters of contrast-enhanced ultrasonography in evaluating cervical cancer metastasis and expression of E-cadherin. Oncology Letters 2017 Aug 22 ELISA Human blood

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