• Gene Name：
• IL17A

• Protein Name：
• Interleukin-17A

• Human Gene Id：
• 3605

• Human Swiss Prot No：
• Q16552

• Mouse Swiss Prot No：
• Q62386

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• IL17A;CTLA8;IL17;Interleukin-17A;IL-17;IL-17A;Cytotoxic T-lymphocyte-associated antigen 8;CTLA-8

• Detection Method：
• Colorimetric

• Background：
• function:Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.,online information:Interleukin-17 entry,PTM:Found both in glycosylated and nonglycosylated forms.,similarity:Belongs to the IL-17 family.,subunit:Homodimer.,tissue specificity:Restricted to activated memory T-cells.,

• Function：
• regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein amino acid glycosylation, apoptosis, defense response, inflammatory response, immune response, cell-cell signaling,cell death, glycoprotein metabolic process, glycoprotein biosynthetic process, response to wounding, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, programmed cell death, death, positive regulation of cellular biosynthetic process, biopolymer glycosylation, regulation of transcription, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA p

• Subcellular Location：
• Secreted .

• Expression：
• Expressed in memory Th17 cells (at protein level).

MiR-150-5p regulates EGR2 to promote the development of chronic rhinosinusitis via the DC-Th axis. INTERNATIONAL IMMUNOPHARMACOLOGY 2017 Nov 16 ELISA Human dendritic cells (DCs)

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