• Gene Name：
• CSF2

• Protein Name：
• Granulocyte-macrophage colony-stimulating factor

• Human Gene Id：
• 1437

• Human Swiss Prot No：
• P04141

• Mouse Swiss Prot No：
• P01587

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• CSF2;GMCSF;Granulocyte-macrophage colony-stimulating factor;GM-CSF;Colony-stimulating factor;CSF;Molgramostin;Sargramostim

• Detection Method：
• Colorimetric

• Background：
• function:Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.,online information:Clinical information on Leukine,pharmaceutical:Available under the names Leukine (Immunex) and Leucomax (Novartis). Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.,polymorphism:Variant Ile-117 may be a risk factor for atopic asthma.,similarity:Belongs to the GM-CSF family.,subunit:Monomer.,

• Function：
• myeloid dendritic cell activation, cell activation, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, myeloid leukocyte activation, immune system development, leukocyte differentiation, myeloid leukocyte differentiation, regulation of DNA replication, anti-apoptosis, immune response,positive regulation of cell proliferation, positive regulation of biosynthetic process, positive regulation of signal transduction, positive regulation of macromolecule biosynthetic process, positive regulation of phosphorus metabolic process, positive regulation of macromolecule metabolic process, regulation of protein kinase cascade, positive regulation of gene expression, positive regulation of cell communication, positive regulation of protein kinase cascade,regulation of foam cell differentiation, positive regulation of foam cell differentiation,

• Subcellular Location：
• Secreted .

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