• Gene Name：
• EGF

• Protein Name：
• Pro-epidermal growth factor

• Human Gene Id：
• 1950

• Human Swiss Prot No：
• P01133

• Mouse Swiss Prot No：
• P01132

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• EGF;Pro-epidermal growth factor;EGF

• Detection Method：
• Colorimetric

• Background：
• disease:Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4) [MIM:611718]; also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes.,function:EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.,online information:Epidermal growth factor entry,similarity:Contains 9 EGF-like domains.,similarity:Contains 9 LDL-receptor class B repeats.,tissue specificity:Expressed in kidney, salivary gland, cerebrum and prostate.,

• Function：
• MAPKKK cascade, activation of MAPKK activity, angiogenesis, blood vessel development, morphogenesis of a branching structure, regulation of protein amino acid phosphorylation, vasculature development, DNA metabolic process, DNA replication, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process,regulation of mitosis, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, epidermal growth factor receptor signaling pathway, regulation of epidermal growth factor receptor activity, intracellular signaling cascade, protein kinase cascade, regulation of mitotic cell cycle, positive regulation of cell proliferation, positive regulation of signal transduction, regulation of receptor activity, positive regulation of phosphorus metabolic process, reg

• Subcellular Location：
• Membrane; Single-pass type I membrane protein.

• Expression：
• Expressed in kidney, salivary gland, cerebrum and prostate.

Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages Journal of Inflammation Research Fubing Shen ELISA Human

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs