• Gene Name：
• CNTF

• Protein Name：
• Ciliary neurotrophic factor

• Human Gene Id：
• 1270

• Human Swiss Prot No：
• P26441

• Mouse Swiss Prot No：
• P51642

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• CNTF;Ciliary neurotrophic factor;CNTF

• Detection Method：
• Colorimetric

• Background：
• disease:Overexpressed in most acute myelogenous leukemia (AML) cases (27 over 29).,function:CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.,function:May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis.,online information:Ciliary neurotrophic factor entry,similarity:Belongs to the CNTF family.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Homodimer.,tissue specificity:Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific.,tissue specificity:Nervous system.,

• Function：
• regulation of cell growth, cell activation, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, transcription, protein complex assembly, cellular ion homeostasis, muscle organ development, positive regulation of cell proliferation, regulation of cell size, positive regulation of signal transduction,glial cell differentiation, positive regulation of phosphorus metabolic process, positive regulation of macromolecule metabolic process, regulation of protein kinase cascade, positive regulation of cell communication, positive regulation of cell development, positive regulation of protein kinase cascade, regulation of cell morphogenesis involved in differentiation, regulation of cell death, regulation of neuron projection development, positive regulation of neuron projection development, astrocyte development, regulation of phosphoinosit

• Subcellular Location：
• Cytoplasm.

• Expression：
• Nervous system.

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