Oct-2 (ABT211) IHC kit
- Catalog No.:IHCM6813
- Applications:IHC
- Reactivity:Human;Mouse;
- Target:
- Oct-2
- Fields:
- >>Herpes simplex virus 1 infection;>>Lipid and atherosclerosis
- Gene Name:
- POU2F2 OCT2 OTF2
- Protein Name:
- Oct-2
- Human Gene Id:
- 5452
- Human Swiss Prot No:
- P09086
- Immunogen:
- Synthesized peptide derived from human Oct-2 AA range: 250-350
- Specificity:
- The antibody can specifically recognize human Oct-2 protein.
- Source:
- Mouse, Monoclonal/IgG2b, kappa
- Purification:
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- Storage Stability:
- 2°C to 8°C/1 year
- Other Name:
- POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;Octamer-binding protein 2;Oct-2;Octamer-binding transcription factor 2;OTF-2)
- Background:
- The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
- Function:
- function:Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR and PGR.,tissue specificity:Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147.,
- Subcellular Location:
- Nuclear
- Expression:
- Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
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- Antibody-FAQs
- Products Images
- Human diffuse large B-cell lymphoma tissue was stained with Anti-Oct-2 (ABT211) Antibody
- Human diffuse large B-cell lymphoma tissue was stained with Anti-Oct-2 (ABT211) Antibody
- Human diffuse large B-cell lymphoma tissue was stained with Anti-Oct-2 (ABT211) Antibody
- Human tonsil tissue was stained with Anti-Oct-2 (ABT211) Antibody
- Human tonsil tissue was stained with Anti-Oct-2 (ABT211) Antibody