Oct-2 (ABT211) IHC kit

    • Catalog No.:IHCM6813
    • Applications:IHC
    • Reactivity:Human;Mouse;
      • Target:
      • Oct-2
      • Fields:
      • >>Herpes simplex virus 1 infection;>>Lipid and atherosclerosis
      • Gene Name:
      • POU2F2 OCT2 OTF2
      • Protein Name:
      • Oct-2
      • Human Gene Id:
      • 5452
      • Human Swiss Prot No:
      • P09086
      • Immunogen:
      • Synthesized peptide derived from human Oct-2 AA range: 250-350
      • Specificity:
      • The antibody can specifically recognize human Oct-2 protein.
      • Source:
      • Mouse, Monoclonal/IgG2b, kappa
      • Purification:
      • The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
      • Storage Stability:
      • 2°C to 8°C/1 year
      • Other Name:
      • POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;Octamer-binding protein 2;Oct-2;Octamer-binding transcription factor 2;OTF-2)
      • Background:
      • The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
      • Function:
      • function:Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR and PGR.,tissue specificity:Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147.,
      • Subcellular Location:
      • Nuclear
      • Expression:
      • Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
      • Products Images
      • Human diffuse large B-cell lymphoma tissue was stained with Anti-Oct-2 (ABT211) Antibody
      • Human diffuse large B-cell lymphoma tissue was stained with Anti-Oct-2 (ABT211) Antibody
      • Human diffuse large B-cell lymphoma tissue was stained with Anti-Oct-2 (ABT211) Antibody
      • Human tonsil tissue was stained with Anti-Oct-2 (ABT211) Antibody
      • Human tonsil tissue was stained with Anti-Oct-2 (ABT211) Antibody