• Target：
• PANX1

• Gene Name：
• PANX1 MRS1 UNQ2529/PRO6028

• Protein Name：
• Pannexin-1

• Human Gene Id：
• 24145

• Human Swiss Prot No：
• Q96RD7

• Mouse Gene Id：
• 55991

• Mouse Swiss Prot No：
• Q9JIP4

• Rat Gene Id：
• 315435

• Rat Swiss Prot No：
• P60570

• Immunogen：
• Synthesized peptide derived from human C-ternal PANX1

• Specificity：
• This antibody detects endogenous levels of PANX1 at Human, Mouse,Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000 IHC 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Pannexin-1

• Molecular Weight(Da)：
• 47kD

• Function：
• Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation . May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis . Plays a critical role in oogenesis .

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Endoplasmic reticulum membrane ; Multi-pass membrane protein .

• Expression：
• Widely expressed (PubMed:30918116). Highest expression is observed in oocytes and brain (PubMed:30918116). Detected at very low levels in sperm cells (PubMed:30918116).

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