S43A3 rabbit pAb

  • Catalog No.:YT8108
  • Applications:IHC;WB
  • Reactivity:Human;Mouse
    • Target:
    • SLC43A3
    • Gene Name:
    • SLC43A3 PSEC0252
    • Protein Name:
    • Solute carrier family 43 member 3 (Protein FOAP-13)
    • Human Swiss Prot No:
    • Q8NBI5
    • Mouse Swiss Prot No:
    • A2AVZ9
    • Immunogen:
    • Synthesized peptide derived from human C-ternal S43A3
    • Specificity:
    • This antibody detects endogenous levels of S43A3 at Human, Mouse
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000 IHC 1:50-200
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Solute carrier family 43 member 3 (Protein FOAP-13)
    • Molecular Weight(Da):
    • 54kD
    • Function:
    • Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine . May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity). ; [Isoform 1]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane . ; [Isoform 2]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane .
    • Subcellular Location:
    • Basolateral cell membrane ; Multi-pass membrane protein .
    • Expression:
    • Widely expressed with highest levels in the liver and lung, followed by the pancreas (PubMed:26455426). Highly expressed in macrophages (Ref.1).