• Target：
• FKB10

• Gene Name：
• FKBP10 FKBP65 PSEC0056

• Protein Name：
• FKB10

• Human Gene Id：
• 60681

• Human Swiss Prot No：
• Q96AY3

• Mouse Gene Id：
• 14230

• Mouse Swiss Prot No：
• Q61576

• Immunogen：
• Synthesized peptide derived from human FKB10 AA range: 339-389

• Specificity：
• This antibody detects endogenous levels of FKB10 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 64kD

• Background：
• The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009],

• Function：
• catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin, but not by cyclosporin A.,function:PPIases accelerate the folding of proteins during protein synthesis.,PTM:Glycosylated and phosphorylated.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 2 EF-hand domains.,similarity:Contains 4 PPIase FKBP-type domains.,

• Subcellular Location：
• Endoplasmic reticulum lumen .

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