• Target：
• NEO1

• Fields：
• >>TGF-beta signaling pathway;>>Axon guidance;>>Cell adhesion molecules

• Gene Name：
• NEO1 IGDCC2 NGN

• Protein Name：
• NEO1

• Human Gene Id：
• 4756

• Human Swiss Prot No：
• Q92859

• Mouse Swiss Prot No：
• P97798

• Rat Swiss Prot No：
• P97603

• Immunogen：
• Synthesized peptide derived from human NEO1 AA range: 82-132

• Specificity：
• This antibody detects endogenous levels of NEO1 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 161kD

• Background：
• This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

• Function：
• alternative products:Additional isoforms seem to exist,function:May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues.,similarity:Belongs to the immunoglobulin superfamily. DCC family.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 6 fibronectin type-III domains.,tissue specificity:Widely expressed and also in cancer cell lines.,

• Subcellular Location：
• Cell membrane; Single-pass type I membrane protein.

• Expression：
• Widely expressed and also in cancer cell lines.

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