NEO1 rabbit pAb
- Catalog No.:YT7169
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- NEO1
- Fields:
- >>TGF-beta signaling pathway;>>Axon guidance;>>Cell adhesion molecules
- Gene Name:
- NEO1 IGDCC2 NGN
- Protein Name:
- NEO1
- Human Gene Id:
- 4756
- Human Swiss Prot No:
- Q92859
- Mouse Swiss Prot No:
- P97798
- Rat Swiss Prot No:
- P97603
- Immunogen:
- Synthesized peptide derived from human NEO1 AA range: 82-132
- Specificity:
- This antibody detects endogenous levels of NEO1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 161kD
- Background:
- This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
- Function:
- alternative products:Additional isoforms seem to exist,function:May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues.,similarity:Belongs to the immunoglobulin superfamily. DCC family.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 6 fibronectin type-III domains.,tissue specificity:Widely expressed and also in cancer cell lines.,
- Subcellular Location:
- Cell membrane; Single-pass type I membrane protein.
- Expression:
- Widely expressed and also in cancer cell lines.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night