GSTO2 rabbit pAb

    • Catalog No.:YT7139
    • Applications:WB
    • Reactivity:Human;Mouse;Rat
      • Target:
      • GSTO2
      • Fields:
      • >>Glutathione metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Drug metabolism - other enzymes;>>Metabolic pathways;>>Platinum drug resistance;>>Pathways in cancer;>>Chemical carcinogenesis - DNA adducts;>>Chemical carcinogenesis - receptor activation;>>Chemical carcinogenesis - reactive oxygen species;>>Hepatocellular carcinoma;>>Fluid shear stress and atherosclerosis
      • Gene Name:
      • GSTO2
      • Protein Name:
      • GSTO2
      • Human Swiss Prot No:
      • Q9H4Y5
      • Mouse Swiss Prot No:
      • Q8K2Q2
      • Immunogen:
      • Synthesized peptide derived from human GSTO2 AA range: 70-120
      • Specificity:
      • This antibody detects endogenous levels of GSTO2 at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 27kD
      • Background:
      • The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010],
      • Function:
      • catalytic activity:RX + glutathione = HX + R-S-glutathione.,similarity:Belongs to the GST superfamily. Omega family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,tissue specificity:Expressed in a range of tissues, including the liver, kidney, skeletal muscle and prostate. Strongest expression in the testis.,
      • Subcellular Location:
      • cytoplasm,cytosol,extracellular exosome,
      • Expression:
      • Expressed in a range of tissues, including the liver, kidney, skeletal muscle and prostate. Strongest expression in the testis.
      • Products Images
      • Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night