DPY30 rabbit pAb
- Catalog No.:YT7083
- Applications:IHC;IF
- Reactivity:Human;Mouse;Rat
- Target:
- DPY30
- Gene Name:
- DPY30
- Protein Name:
- DPY30
- Human Gene Id:
- 84661
- Human Swiss Prot No:
- Q9C005
- Mouse Gene Id:
- 66310
- Mouse Swiss Prot No:
- Q99LT0
- Rat Gene Id:
- 286897
- Rat Swiss Prot No:
- Q8K3E7
- Immunogen:
- Synthesized peptide derived from human DPY30 AA range: 39-89
- Specificity:
- This antibody detects endogenous levels of DPY30 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 11kD
- Background:
- This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016],
- Function:
- similarity:Belongs to the dpy-30 family.,subunit:Component of MLL-containing complexes (named MLL, ASCOM, MLL2/MLL3 or MLL3/MLL4 complex): at least composed ASH2L, RBBP5, DPY30, WDR5, one or several histone methyltransferases (MLL, MLL2, MLL3 and/or MLL4), and the facultative components MEN1, HCFC1, HCFC2, NCOA6, KDM6A, PAXIP1/PTIP and C16orf53/PA1.,
- Subcellular Location:
- Nucleus . Golgi apparatus, trans-Golgi network . Associated with chromatin at regions enriched in histone H3 trimethylated at 'Lys-4. Highly enriched in gene promoter regions and 5' UTRs, but not in downstream regions of genes or 3' UTRs (By similarity). .
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).