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- FBXL5 rabbit pAb
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FBXL5 rabbit pAb
- Catalog No.:YT6983
- Applications:WB
- Reactivity:Human;Mouse
- Gene Name:
- FBXL5 FBL4 FBL5 FLR1
- Immunogen:
- Synthesized peptide derived from human FBXL5 AA range: 319-369
- Specificity:
- This antibody detects endogenous levels of FBXL5 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 76kD
- Background:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010],
- Function:
- function:Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.,similarity:Contains 1 F-box domain.,similarity:Contains 4 LRR (leucine-rich) repeats.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,
- Subcellular Location:
- Cytoplasm, perinuclear region .
![](/uploadfiles/PIC/YT6983wb-2019.jpg)
- Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night