• Target：
• FBXL5

• Gene Name：
• FBXL5 FBL4 FBL5 FLR1

• Protein Name：
• FBXL5

• Human Gene Id：
• 26234

• Human Swiss Prot No：
• Q9UKA1

• Mouse Gene Id：
• 242960

• Mouse Swiss Prot No：
• Q8C2S5

• Immunogen：
• Synthesized peptide derived from human FBXL5 AA range: 319-369

• Specificity：
• This antibody detects endogenous levels of FBXL5 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 76kD

• Background：
• This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010],

• Function：
• function:Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.,similarity:Contains 1 F-box domain.,similarity:Contains 4 LRR (leucine-rich) repeats.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,

• Subcellular Location：
• Cytoplasm, perinuclear region .

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