SRGP2 rabbit pAb
- Catalog No.:YT6865
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- SRGP2
- Fields:
- >>Axon guidance
- Gene Name:
- SRGAP2 ARHGAP34 FNBP2 KIAA0456 SRGAP2A
- Protein Name:
- SRGP2
- Human Gene Id:
- 23380
- Human Swiss Prot No:
- O75044
- Mouse Gene Id:
- 14270
- Mouse Swiss Prot No:
- Q91Z67
- Rat Swiss Prot No:
- D4A208
- Immunogen:
- Synthesized peptide derived from human SRGP2 AA range: 476-526
- Specificity:
- This antibody detects endogenous levels of SRGP2 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 118kD
- Background:
- This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014],
- Function:
- function:Putative GTPase-activating protein for Rho family small GTPases.,similarity:Contains 1 FCH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,subunit:Probably interacts with ROBO1.,tissue specificity:Expression at low levels in placenta, kidney, and ovary, and little or no expression in all other tissues tested.,
- Subcellular Location:
- Cell membrane . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Cell junction, synapse, postsynaptic cell membrane . Cell projection, lamellipodium . Cytoplasmic vesicle, phagosome . Nucleus . Cytoplasm, cytosol . Recruited to actin-rich phagosomes during phagocytosis (By similarity). Translocates from nucleus to cytoplasm during development (By similarity). .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from CACO2 cells, primary antibody was diluted at 1:1000, 4°over night