SPSY rabbit pAb
- Catalog No.:YT6695
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse
- Target:
- SPSY
- Fields:
- >>Cysteine and methionine metabolism;>>Arginine and proline metabolism;>>Glutathione metabolism;>>Metabolic pathways
- Gene Name:
- SMS
- Protein Name:
- SPSY
- Human Gene Id:
- 6611
- Human Swiss Prot No:
- P52788
- Mouse Gene Id:
- 20603
- Mouse Swiss Prot No:
- P97355
- Immunogen:
- Synthesized peptide derived from human SPSY AA range: 81-131
- Specificity:
- This antibody detects endogenous levels of SPSY at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 40kD
- Background:
- This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],
- Function:
- catalytic activity:S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.,disease:Defects in SMS are the cause of Snyder-Robinson syndrome (SRS) [MIM:309583]; also called X-linked mental retardation Snyder-Robinson type. SRS is characterized by moderate intellectual deficit, hypotonia, an unsteady gait, osteoporosis, kyphoscoliosis and facial asymmetry. Transmission is X-linked recessive.,domain:Composed of 3 domains: the N-terminal domain has structural similarity to S-adenosylmethionine decarboxylase, the central domain is made up of four beta strands and the C-terminal domain is similar in structure to spermidine synthase. The N- and C-terminal domains are both required for activity.,function:Required for normal viability, growth and fertility.,pathway:Amine and polyamine biosynthesis; spermine biosynthesis; spermine from spermidine: step 1/1.,similarity:Belongs to
- Subcellular Location:
- cytosol,extracellular exosome,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- May 20-2022
- Cell-Based ELISA│解您多样本WB检测之困扰
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from CACO2 cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).